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HISTORY
JOHNE'S INFORMATION CENTER - University of Wisconsin Ñ School of Veterinary Medicine

HISTORY
AT A GLANCE

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Before 1910
1910 - 1930
1930 - 1950
1950 - 1970
1970 - 1990
1990 - Present


 
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Armed with new diagnostic tools, scientists found the infection to be in many countries and many animal species. Experimental infection studies discovered the surprising age-dependent susceptibility to M. paratuberculosis infection.

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Table Bottom
Paratuberculosis was described in South America and on the Indian continent during the 1930s,thereby completing evidence of the worldwide distribution of the disease. That decade brought about a broader realization that paratuberculosis jeopardized the cattle industry. A major achievement of the 1930s was the observation of age-dependent resistance of animals to infection by M. paratuberculosis.

In the 1940s, paratuberculosis was recognized to be a problem not only in domesticated livestock, but in wildlife as well. Paratuberculosis was observed to have many similarities with human leprosy. Continued evaluation of diagnostic tests led to the discovery of cross-reactivity, resulting in false-positive tests, with bacteria in the genus Corynebacterium and other antigenically-related bacteria.