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JOHNE'S INFORMATION CENTER - University of Wisconsin Ñ School of Veterinary Medicine
University of Wisconsin - School of Veterinary MedicineUniversity of Wisconsin - School of Veterinary Medicine


Johne's disease can be controlled in farmed bison herds. Find the infection as soon as possible, keep good records, and make sure the calves have no chance to swallow MAP-contaminated milk, colostrum, hay or water.

Control is easy, it just takes time.


(Updated 3/2010)


It takes patience and consistent management to control Johne's disease once it is established in a bison herd. The good news is that it can be done and management changes recommended for Johne's disease control will also help control many other infectious diseases

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bison dam with calfJohne's disease can be controlled and even eliminated from infected herds. However, it takes a thorough understanding of the disease by animal owners, consultation with a veterinarian, and requires use of one or more of the available bison diagnostic tests. Half-hearted attempts to control Johne's disease will generally fail. Control of Johne's disease also takes time and a strong commitment to management practices focused on keeping young animals away from contaminated manure, milk, water, etc. A typical herd clean-up program may take a number of years. Faster clean-up programs are possible, but they are usually more expensive. The basics of control are simple: new infections must be prevented, and animals with the infection must be identified and removed from the herd. 

Remember that the infection can spread from one ruminant species to another, so assess the risk of infection for all your young ruminant animals.

graph of Johnes control programsA computer simulation model illustrates that faster Johne's control can be accomplished by changing both bison rearing procedures and testing the adult herd to identify and cull the infectious animals. Of these two basic strategies, changing cow management to limit the chance of calves becoming infected (swallowing the organism) is the most important.

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header #1 prevent new infection byPrevent new infections in calves through:

. . . manure management

The most MAP bacteria excreted by infected ruminants are in the feces (manure). Farm sanitation and control over where manure goes on a farm are critical to control of Johne's disease. Because of the susceptibility of calves to MAP infection, it is important to keep them well away from adult bison manure that may harbor the infection at least for the first 6 months of life, the "window" of maximum susceptibility.

Calves should be born in a clean dry environment with minimal fecal contamination. Individual birthing pens or paddocks are optimal but if not feasible, you may establish test-negative and test-positive pens (you could test all your adult animals a few months ahead of time to have this test information available).  Then try to establish an area outside the pen free of adult manure contamination (“the safe zone”) for calves from test-negative dams.

Manure contamination of water supplies must be avoided to limit spread of the infection, particularly ponds or streams that young animals can drink from.  If you use water troughs, when cleaning them remove the sediment at the bottom and dump it away from where animals might graze – MAP apparently survives for a long time in this substrate.

Liquid manurePasture contamination with MAP is also important as a means of infection transmission, but it is less so than other modes of transmission and far more difficult to control. Till contaminated pastures and wait for time and environmental conditions (repeated changes in temperature, minimize shaded soil by cutting grass/crops/shrubs) to kill off MAP on fields. While a majority of the organisms die within three months, a small population can remain for up to a year.  Put off stocking contaminated pasture with young animals as long as feasible. Be aware of what the pasture was used for before putting your youngstock on the premises.  Farmed bison are often grazed on fields that had been used for dairy cattle -  MAP infection is a common problem for dairies.

Read about survival of MAP in the environment in the "Biology of MAP" section of this site.

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. . . milk and colostrum management

Many animals infected with MAP will excrete the bacterium in their milk. This happens most often in animals showing clinical signs of Johne's disease, but also occurs in infected animals that still appear healthy.

If you need to bottle-feed a calf, use pasteurized milk or milk replacer. A recent study saw no difference in the number of new cases of Johne’s disease arising in dairy herds (cattle) between those that pasteurized and those that used milk replacer. Recommended protocols: 145°F (63°C) for 30 minutes for batch pasteurization, or 162°F (72°C) for 15 seconds for flash pasteurization.  The milk should be stirred or otherwise in motion to ensure even heat distribution.) Pasteurization kills virtually all MAP that may contaminate raw milk as well as other viral and bacterial agents that could affect the calf’s health.

Colostrum, the antibody-rich milk produced in the first few days after giving birth, also can contain MAP. Because colostrum is critical to the health and survival of newborns, feeding colostrum must be done.

While these articles focus on cattle, they are excellent sources of information and can be found in the "Articles and Brochures" section of this website. Three articles in particular to read are:

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. . . culling offspring of infected mothers

MAP infections can be transmitted from mothers to offspring by contact with the mother's infected feces, through infected colostrum or milk from the mother, or across the placenta into the fetus before the calf is born. Depending on the extent to which manure management and milk/colostrum management recommendations listed above can be implemented, there is a moderate to high probability that calves born to MAP-infected mothers will acquire the infection. Consequently, on a case by case basis, it may be wise to cull offspring born to infected mothers. If not culled, it may take two or more years to determine if the young animal became infected, and this will be time lost in pursuit of control or eradication of the MAP in the herd.

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#2 Identify and remove infected animalsIdentify and remove infected animals:

Test-and-cull program

The majority of MAP infections in a herd are "invisible". Bison with clinical signs of Johne's disease (diarrhea and weight loss) are only a small fraction of the infected animals in a herd. The infection may silently spread from bison to calves long before signs of illness in infected animals are evident. For this reason, laboratory tests are important to determine which bison are infected. Test-positive bison are generally those most likely to be infectious (excreting MAP in milk and manure) and so they should be removed, or at least isolated from, the herd.

Referred to as a test-and-cull program, this practice is essential to successful control of Johne's disease in herds in a reasonable period of time. Decisions on how best to implement testing in a Johne's control program should be made in consultation with your veterinarian. For details about available laboratory tests for Johne's disease, see the bison diagnosis section of this web site.

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MAP is resistant to most disinfectants; washable tools, troughs, and feed dishes may be treated as directed on the bottle with a disinfectant labeled as “tuberculocidal”. Since organic material deactivates the disinfectant, items should thoroughly cleaned with soap and water, rinsed and dried before the disinfectant is applied. Tuberculocidal disinfectants usually contain strong chemical compounds and should be used carefully. The instructions provided on the label for proper use and safe handling should be followed precisely.

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No Johne’s disease vaccines are commercially available for bison.