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HISTORY
JOHNE'S INFORMATION CENTER - University of Wisconsin Ñ School of Veterinary Medicine
University of Wisconsin - School of Veterinary MedicineUniversity of Wisconsin - School of Veterinary Medicine
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Giant cell
Line Giant cells result from fusion of several macrophages. Such cells are a hallmark of granulomatous inflammation and typical of the host response to M. paratuberculosis infection. The specific type giant cells most often seen in Johne's disease are called Langhan’s giant cells.

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