SUMMARY: Regulations regarding the interstate movement of domestic animals that have reacted to a test for paratuberculosis were amended. First, they replaced all references to ‘‘paratuberculosis’’ with references to ‘‘Johne’s disease’’ to reflect a change in nomenclature. Second, they identified an official test for the detection of Johne’s disease in domestic animals. Third, they amended the requirements for moving animals interstate. These actions updated the regulations and removed restrictions on the interstate movement of animals that are positive to an official Johne’s disease test that did not appear necessary to prevent the interstate spread of Johne’s disease.